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Clinical Trials/NCT04451707
NCT04451707
Completed
N/A

Multicentre Retrospective Study on the Clinical and Epidemiological Characteristics and Therapeutic Management of Non-cholera Vibrio Infections

Groupe Hospitalier de la Rochelle Ré Aunis7 sites in 1 country67 target enrollmentMarch 12, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
Vibrio Infections
Sponsor
Groupe Hospitalier de la Rochelle Ré Aunis
Enrollment
67
Locations
7
Primary Endpoint
Number of Participants With Diagnosed Non-cholerae or Non-O1/O139 Vibrio Infection
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The purpose of this study is to identify the epidemiological and clinical characteristics of patients diagnosed with non-cholera Vibrio infection in Western France from 2000 to 2019.

Detailed Description

Vibrios are gram-negative, ubiquitous bacteria of the marine flora and are found particularly in warm waters. For example, the incidence is high in Florida and Vibrio infections are now reportable in the United States. Different species of Vibrio are described. A distinction is made between choleric vibrios belonging to serogroups O1 and O139, responsible for cholera epidemics, and non-choleric vibrios. Our study will focus on non-cholera vibrios. Vibrio infections can occur by eating contaminated raw seafood or by exposure of a wound to the marine environment. They occur mainly during the hot summer months. This can be explained on the one hand by higher water temperature and on the other hand by increased beach use. With global warming, it is possible that Vibrio infections may increase in number and location.

Registry
clinicaltrials.gov
Start Date
March 12, 2020
End Date
June 17, 2020
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Groupe Hospitalier de la Rochelle Ré Aunis
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • non-cholera Vibrio infection

Exclusion Criteria

  • vibriosis to Vibrio cholerae O1 and O139

Outcomes

Primary Outcomes

Number of Participants With Diagnosed Non-cholerae or Non-O1/O139 Vibrio Infection

Time Frame: Up to 20 years, from 2000-2019

A non-cholerae or non-O1/O139 Vibrio infection was defined by a biological sample (blood, superficial sample, deep sample, and ear sample) positive to a Vibrio species other than Vibrio cholerae O1-O139.

Secondary Outcomes

  • Number of Participants Associated With Environmental Factors(at inclusion)
  • Number of Participants Per Identified Species(at inclusion)
  • Number of Participants by Month of the Years(at inclusion)
  • Number of Participants Treated by Antibiotics(through study completion, an average of 1 month)
  • Number of Patients Per Clinical History(at inclusion)
  • Number of Participants Per Outcome(through study completion, an average of 1 month)

Study Sites (7)

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