Effects on endothelial progenitor cells by statins in all with acute coronary syndrome

Phase 1

• Conditions: Acute Coronary syndrome; MedDRA version: 19.0Level: PTClassification code 10051592Term: Acute coronary syndromeSystem Organ Class: 10007541 - Cardiac disorders; Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]

• Registration Number: EUCTR2016-000355-27-GB
• Lead Sponsor: niversity Hospitals of North Midlands NHS Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-12-08
• Last Update Posted: 12 December 2016

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Patient-participants will be eligible for the study if they are;
1.1.Admitted with an acute coronary syndrome
2.Are statin naïve or receiving a statin other than atorvastatin, or atorvastatin at a dose less than 80mg daily.
3.Able to give informed consent
4.Have undergone coronary angiography / plasty
5.Able to attend follow up visits

Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 30
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 10

Exclusion Criteria

Patient-participants will be excluded if
1.Atorvastatin is contraindicated (e.g. allergic to excipient)
2.Women of child bearing potential unless they are using a recognised effective form of contraception or are not sexually active, and have no intention of becoming sexually active during the course of the trial.
3.Women who are breastfeeding

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified