Study on acupuncture anesthesia assisted with percutaneous CT guided microwave ablation probe in the treatment of lung cancer

Phase 1

Recruiting

• Conditions: lung cancer

• Registration Number: ITMCTR2000003792
• Lead Sponsor: Shanghai Pulmonary Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

1. No gender limit, age 18-80 years old;
2. Chest CT showed pulmonary nodules, and the nodules were ground glass nodules or solid nodules with the size of 5mm to 30mm;
3. It was confirmed by pathology as primary malignant tumor of lung, and had not received corresponding treatment.
4. Patients with early or very early lung cancer who are unable to undergo surgery or are unwilling to undergo surgery due to moderate or severe lung function decline.
5. The function of the main organs is normal, that is to say, it meets the following standards:
The blood routine examination standard should meet the following requirements:
HB >= 120g / L (no blood transfusion within 14 days);
ANC >= 2.0 x 10^9/L;
PLT >= 100 x 10^9/L;
Biochemical examination should meet the following standards:
Bil < 1.25 times upper limit of normal value (ULN);
ALT and AST < 1.5 x ULN;
Serum Cr <= 1 x ULN, endogenous creatinine clearance rate > 50ml / min (Cockcroft Gault formula)
6. ECoG score 0-1;
7. The expected survival time was more than 1 year.

Exclusion Criteria

1. Active tuberculosis (TB);
2. Abnormal coagulation function (PT > 16 S, APTT > 43 s, TT > 21 s, FBG < 2 g / L), bleeding tendency (such as active peptic ulcer) or undergoing thrombolytic or anticoagulant therapy;
3. Grade IV congestive heart failure (NYHA classification), poorly controlled and clinically significant arrhythmias and / or acute myocardial infarction within 3 months;
4. Patients with hematologic disease or other malignant tumors were not cured;
5. Pregnant women;
6. Mental patients;
7. The expected survival time was less than 1 year;
8. Chest spiral CT showed lung lesions or complete atelectasis, double lung bullae larger than 1 / 3 of the lobes;
9. ECoG score was more than 2 points;
10. Unable to cooperate or refuse to receive treatment or testing.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
PFS;