Biochemical Marker to Predict the Recurrence of Atrial Fibrillation After Surgical Maze Procedure

Completed

• Conditions: Atrial Fibrillation

• Registration Number: NCT00542659
• Lead Sponsor: Samsung Medical Center

Brief Summary

The role of plasma NT-proBNP, hsCRP, TIMP-1(Tissue inhibitors of MetalloProteinase-1),TGF-b, MMP-3(Matrix MetalloProteinase-3), and pro-MMP-1 in predicting the recurrence of AF after surgical Maze procedure.

The association of expression of CTGF, TGF-b, BNP, ANP, collagen-1, and collagen-3 in LA with the recurrence of AF after surgical Maze procedure.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-02
• Study First Submitted: 2007-10-10
• Study First Submitted QC: 2007-10-10
• Study First Posted: 2007-10-11
• Primary Completion: 2007-12
• Study Completion: 2008-02
• Status Verified: 2011-07
• Last Update Submitted: 2011-07-22
• Last Update Posted: 2011-07-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 86

Inclusion Criteria

• The patients who have valvular heart disease with atrial fibrillation and are scheduled for operation

Exclusion Criteria

• Coronary heart disease
• Congestive heart failure

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
AF recurrence	year

Trial Locations

Locations (1)

Samsung Medical Center; 🇰🇷 Seoul, Korea, Republic of