Effect of mechanical ventilation on oxynation and hemodynamic in head trauma.

Not Applicable

• Conditions: Head trauma.; Other intracranial injuries, Intracranial injury with prolonged coma,Traumatic subarachnoid haemorrhage,Traumatic subdural haemorrhage,Diffuse brain injury,Focal brain injury,Epidural haemorrhage,; s06.2, s06

• Registration Number: IRCT2016080729234N1
• Lead Sponsor: Vice Chancellor for research of Sabzevar University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

age between 15 and 60 years; patients suffering from traumatic brain injuries who are intubated and are under mechanical ventilation with SIMV mode; stable hemodynamic (MAP more than 70 mm Hg for at least 30 minutes before the start of the study); Glasgow Coma Scale <9 ; no history of chronic obstructive pulmonary disease (COPD); Exclusion criteria: unstable hemodynamic (MAP <70); need to CPR.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pressure of arterial oxygen. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Atrial blood gas (ABG).;Pressure of arterial CO2. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Atrial blood gas (ABG).;Aterial oxygen saturation. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Monitore.

Secondary Outcome Measures

Name	Time	Method
Mean artery pressure. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Sphygmomanometer.;Heart rate. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Number in minute.;Systolic pressure. Timepoint: Before intervention, half an hour and 2 hours after intervention. Method of measurement: Sphygmomanometer.