Osteoporosis and ovarian function in premenopausal cervical cancer patients who underwent bilateral oophorectomy or concurrent chemo-radiotherapy

Phase 3

Completed

• Conditions: Premenopausal cervical cancer patients who underwent bilateral oophorectomy or CCRT; Cervical cancer; Pre-menopause; Bone density; Ovarian function; Oophorectomy; Concurrent Chemoradiotherapy

• Registration Number: TCTR20201223003
• Lead Sponsor: one

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-23
• Study Completion: 2021-07-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

Post complete treatment 1-10 yr
Age below 50 yr
Regular menstruation
Underwent bilateral oophorectomy or CCRT
No history of invasive cervical cancer to bone
No history use of steroid drug
No history of other cancer, hyperthyroidism, rheumatoid arthritis and fracture

Exclusion Criteria

None

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation of osteoporosis and ovarian function in premenopausal cervical cancer patients Post complete treatment 1-10 yr Bone mineral density at lumbar and hip, serum FSH, serum Estrdiol

Secondary Outcome Measures

Name	Time	Method
Correlation of cervical cancer treatments and osteoporosis Post complete treatment 1-10 yr Bone mineral density at lumbar and hip