NCT06339489招募中不适用
Explore the Bone Metabolism Characteristics of Premature Ovarian Insufficiency
Shi Yun1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年4月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- tartrate resistant acid phosphatase-5b, TRACP-5b
研究概览
简要总结
Explore the bone metabolism characteristics of premature ovarian insufficiency.
详细描述
Explore the bone metabolism characteristics of premature ovarian insufficiency, indexes includes serum levels of TRACP-5b and BALP, BMD values of lumbar spine L1-L4, left and right hip, left and right femoral neck et.al.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 39 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed by Western medicine with premature ovarian insufficiency. 18 ≤ patients' age ≤ 39 years;. Patients who voluntarily participate in this study, sign an informed consent form.
排除标准
- •Patients with congenital gonadal dysplasia or a family history similar to "early menopause".
- •POI patients with acquired organic lesions or ovarian surgery. Patients who have taken Western or herbal medicine artificial cycle therapy or other endocrine therapy in the past three months.
- •Patients with serious primary diseases and mental disorders such as cardiovascular and cerebrovascular, liver, kidney and hematopoietic system.
- •Patients who are breastfeeding or pregnant.
结局指标
主要结局
tartrate resistant acid phosphatase-5b, TRACP-5b
时间窗: On the 2~4th day of menstruation (amenorrhea patients are collected when enrolled)
Blood samples are collected when enrolled.
次要结局
- bone specific alkaline phosphatase, BALP(On the 2~4th day of menstruation (amenorrhea patients are collected when enrolled))
- bone mineral density, BMD(On the 2~4th day of menstruation (amenorrhea patients are collected when enrolled))
研究者
Shi Yun
Sponsor-Investigator
Dongzhimen Hospital, Beijing
研究点 (1)
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