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The effect of therapy of exjade and desferal on ferritin level in patients with major thalassemia

Phase 2
Conditions
Major Thalassemia.
Beta thalassaemia
Registration Number
IRCT2015042114333N32
Lead Sponsor
Kermanshahu University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
90
Inclusion Criteria

Inclusion: being younger than 18; having thalasemia major based on observing clinical symptoms and hemoglobin electrophoresis history; being treated by deferoxamine hypodermic injection and ferritin level 1000 to 3000. Exclusion:inability to digest exjade; hepatitis virologic; LFT; active hepatitis; noncompliance with previous treatment regimens; ALT and AST normal up to 3 times

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Ferritin serum amount. Timepoint: at the beginning of the study and every 3 month for 6 months. Method of measurement: Using starfax device.
Secondary Outcome Measures
NameTimeMethod
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