Predicting how quickly fluid around the lung will come back after draining

Not Applicable

• Conditions: Malignant pleural effusion; Malignant pleural effusion NOS; Cancer

• Registration Number: ISRCTN16567838
• Lead Sponsor: orfolk and Norwich University Hospitals NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-09-29
• Last Update Posted: 11 September 2023
• Study Completion: 2023-09-26

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 241

Inclusion Criteria

1. Participant is willing and able to give informed consent for participation in the study
2. Aged 18 years or above
3. Diagnosed with pleural effusion on CT or ultrasound (US)
4. Patient attending for therapeutic aspiration (large volume drainage) of their pleural effusion: there is no specific minimal pleural fluid volume but this should be larger than required for diagnosis alone (typically 60 ml is taken for diagnostic purposes)
5. Known or suspected malignancy as the underlying cause of the effusion
6. In the Investigator’s opinion, is able and willing to comply with all study requirements

Exclusion Criteria

1. Patients who are pregnant or lactating
2. Pleural infection or other condition requiring admission and chest drain insertion
3. Known transudative pleural effusion or pleural effusion thought to be primarily due to cardiac, renal or hepatic impairment

Study & Design

• Study Type: Observational
• Study Design: Not specified