Effect of taste and smell on feed tolerance in premature infants
Not Applicable
- Conditions
- Health Condition 1: P073- Preterm [premature] newborn [other]
- Registration Number
- CTRI/2020/02/023412
- Lead Sponsor
- Priyanka Karnani
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Preterm infants less than 32 weeks gestation and less than 1250g birth weight who are hemodynamically stable (blood pressure not requiring boluses or pressors) and could be started on enteral tube feeds within 72 hours of birth.
Exclusion Criteria
1. Infants with evidence or suspicion of any major congenital malformation such as congenital intestinal obstruction or perforation, gastroschisis, large omphalocele, congenital diaphragmatic hernia, chromosomal anomalies or craniofacial malformations.
2. Refusal of parental consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome will be time taken to reach full enteral feeds (in days) calculated from the day tube feeds are initiated.Timepoint: Full feeds will be defined as an enteral intake of 150ml/kg/day, which should be tolerated for at least 48hours.
- Secondary Outcome Measures
Name Time Method 1.Time to reach feed volume of 120 ml/kg/day tolerated for at least 48 hours <br/ ><br>2.Time to reach direct feeds <br/ ><br>3.Feed intolerance <br/ ><br>4.Nil per oral (NPO) hours <br/ ><br>5.Time to regain birth weight <br/ ><br>6.Duration of parenteral nutrition <br/ ><br>7.Growth velocity for weight, length and head circumference at different time points-at the end of primary outcome, at the end of intervention and at discharge <br/ ><br>8.Time to reach discharge criteria and duration of hospital stay <br/ ><br>9.NEC stage 2 and beyond <br/ ><br>10.SepsisTimepoint: During NICU stay at different time point and at discharge