Comparison of the effect of combining botulinum toxin and cross-linked hyaluronic acid with non cross-linked hyaluronic acid in the treatment of icepick acne scar
Phase 3
- Conditions
- icepick acne scar patients.Acne vulgarisL70.0
- Registration Number
- IRCT20210718051930N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
All patients with icepick acne scar in the range of 18 to 40 years
Having informed consent to participate in the study
Possibility to attend visit and follow-up sections
Exclusion Criteria
Active acne
Inflammation or herpes simplex virus infection at the site of the procedure
Taking anticoagulants or NSAIDs within 48 hours before and in patients with platelet dysfunction or thrombocytopenia
Serious internal disease
Accompanying disease at the treatment site
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Qualitative intensity of scar. Timepoint: At the beginning of the study, 1 month later and then 3 and 6 months later. Method of measurement: Photography with Visioface.;Quantitative intensity of scar. Timepoint: At the beginning of the study, 1 month later and then 3 and 6 months later. Method of measurement: Determine the depth of the scar by photography with Visioface.;The rate of improvement in scar. Timepoint: 1 month after starting treatment and then 3 and 6 months later. Method of measurement: according to Global Aesthetic Improvement Scale (GAIS).
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: 1 month after starting treatment and then 3 and 6 months later. Method of measurement: Clinical evaluation.