Evaluation of the clinical consequences of botulonium toxin a compared to medical treatment in patients with urge incontinence

Phase 2

Recruiting

• Conditions: urge incontinence.; Urge incontinence; N39.41

• Registration Number: IRCT20230508058117N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

Accurate diagnosis of patients with urge incontinence based on the diagnosis of a pelvic floor specialist,
women over the age of 18,
suffering from urge incontinence and in the case of a history of non-response to antimuscarinic drugs in the past 3 months;
Urgent incontinence and having a history of antimuscarinic drug complications (constipation, blurred vision, dry mouth)

Exclusion Criteria

Patients with urinary tract infection,
interstitial cystitis,
having an intermittent or permanent catheter
previous pelvic radiotherapy treatment
neurogenic urge incontinence
a history of sensitivity to Botox;
Use of aminoglycoside drugs
contraindications for receiving antimuscarinic treatment (tachyrhythmia, angle-closure glaucoma)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ICIQ-OAB questionnaire score. Timepoint: Before treatment, one week, 1 month after treatment. Method of measurement: Patient's answer.