The effect of injection of Botulinum toxin A on Benign Prostatic Hyperplasia
Phase 2
- Conditions
- Benign Prostatic Hyperplasia.Hyperplasia of prostate
- Registration Number
- IRCT201008174582N1
- Lead Sponsor
- Vice chancellor for research of Guilan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 10
Inclusion Criteria
male patients older than 50 years, patients with BPH refractory to medical therapy and not suitable for surgery, IPSS (International Prostatic Symptom Score) =8. Exclusion criteria: active UTI, previous history of prostate surgery, prostate cancer, acute prostatitis, simultaneous use of drugs such as: Amino glycosides, Cholinergics, Anticholinergics, Androgens, Estrogen, Steroids, history of allergy to BoNT-A, neurologic disease like Parkinson, Myastenia Gravis, Multiple Sclerosis, history of allergy to BoNT.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method International score of prostatic signs & symptoms. Timepoint: before intervention and 3 months after that. Method of measurement: IPSS: International Prostatic Symptom Score.
- Secondary Outcome Measures
Name Time Method Maximum urinary flow. Timepoint: before intervention and 3 months after that. Method of measurement: uroflometry.;Prostate volume. Timepoint: before intervention and 3 months after that. Method of measurement: sonography.