A Monocentric Study for Development and Use of Tomographic Neurofeedback Protocols for Patients Suffering From Chronic Tinnitus
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Tinnitus, Subjective
- Sponsor
- University of Zurich
- Enrollment
- 52
- Locations
- 1
- Primary Endpoint
- Change from Baseline in Tinnitus symptoms assessed by questionnaires
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Chronic tinnitus affects about 10-15% of the population in industrialized countries. Investigations of the brain activity by using electroencephalography (EEG) showed that in localized regions of the hearing system brain activity was decreased. This reduction of activity is thought to be one of the reasons that keep the perception of the tinnitus going. Recent studies have shown that neurofeedback is a viable option for treatment of chronic tinnitus. By using neurofeedback it is possible to train brain functions by the simple principle of rewarding wanted changes and punishing unwanted ones. The purpose of the investigators study is to show the efficacy of specific localized neurofeedback training in comparison to global relaxing neurofeedback training. In order to achieve decreased tinnitus symptoms or even disappearance of the tinnitus, 15 neurofeedback trainings are planned. Before and up to 6 month after the training EEG-recordings are performed.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 18-75
- •Chronic Tinnitus \> 0.5 years
- •Informed Consent
- •Fluent in German language
Exclusion Criteria
- •Psychological and neurological disorders other than tinnitus
- •Drug- or Alcohol abuse
- •Tranquilizer, antiepileptic drugs, antipsychotics or anesthetics intake
- •Impairing hearing loss or Cochlea Implant
Outcomes
Primary Outcomes
Change from Baseline in Tinnitus symptoms assessed by questionnaires
Time Frame: at 1, 3, 6 month follow up
Assessement of the Tinnitus symptoms before and after the Treatment with neurofeedback by different questionnaires tailored for Tinnitus and Quality of life.
Change from Baseline in delta (3-4Hz) and alpha (8-12Hz) frequency band EEG-activity in the auditory cortex
Time Frame: at 1, 3, 6 month follow up
EEG recordings of the trained frequency bands are compared before and after the Intervention in the named time periods
Secondary Outcomes
- Difference in efficacy between Tomographic Neurofeedback (TONF) and Non Tomographic Neurofeedback (NTE) in treatment of tinnitus assessed by tinnitus questionnaires and frequency band EEG-activity measurements (3-4Hz and 8-12Hz) compared to Baseline.(at 1, 3, 6 month follow up)