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UNIVERSITY OF CALIFORNIA, IRVINE

UNIVERSITY OF CALIFORNIA, IRVINE logo
🇺🇸United States
Ownership
Private, Subsidiary
Established
1965-01-01
Employees
10K
Market Cap
-
Website
http://www.uci.edu

Clinical Trials

447

Active:24
Completed:223

Trial Phases

6 Phases

Early Phase 1:15
Phase 1:40
Phase 2:47
+3 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (317 trials with phase data)• Click on a phase to view related trials

Not Applicable
185 (58.4%)
Phase 2
47 (14.8%)
Phase 1
40 (12.6%)
Phase 4
22 (6.9%)
Early Phase 1
15 (4.7%)
Phase 3
8 (2.5%)

HOPE Intervention for Fitness

Not Applicable
Recruiting
Conditions
Diabetes Mellitus Type 2
First Posted Date
2025-08-11
Last Posted Date
2025-08-11
Lead Sponsor
University of California, Irvine
Target Recruit Count
120
Registration Number
NCT07114822
Locations
🇺🇸

UC Irvine, Irvine, California, United States

Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy

Not Applicable
Not yet recruiting
Conditions
Cancer
Neoplasms
First Posted Date
2025-07-18
Last Posted Date
2025-08-15
Lead Sponsor
University of California, Irvine
Target Recruit Count
30
Registration Number
NCT07073807
Locations
🇺🇸

Chao Family Comprehensive Cancer Center and Ambulatory Care building, Irvine, California, United States

🇺🇸

UCI Health Cancer Center - Newport, Newport Beach, California, United States

🇺🇸

UCI Health Pacific Breast Care Center, Newport Beach, California, United States

and more 2 locations

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

Not Applicable
Recruiting
Conditions
Soft-tissue Sarcoma
Triple Negative Breast Cancer
Non-small Cell Lung Cancer
Cervical Cancer
Ovarian Cancer
KRAS Mutation-Related Tumors
Interventions
First Posted Date
2025-07-14
Last Posted Date
2025-07-14
Lead Sponsor
University of California, Irvine
Target Recruit Count
67
Registration Number
NCT07064018
Locations
🇺🇸

Chao Family Comprehensive Cancer Center University of California, Irvine, Orange, California, United States

Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer

Not Applicable
Recruiting
Conditions
Lung Cancer
Driver Mutation
First Posted Date
2025-07-14
Last Posted Date
2025-07-14
Lead Sponsor
University of California, Irvine
Target Recruit Count
1753
Registration Number
NCT07062172
Locations
🇺🇸

Chao Family Comprehensive Cancer Center University of California, Irvine, Orange, California, United States

Umbilical CB-NK Expressing sIL-15 & PD-L1 +/- Atezolizumab in NSCLC Pts Refractory to PD-1/PD-L1

Not Applicable
Not yet recruiting
Conditions
Non-small Cell Lung Cancer
NSCLC
Lung Cancer, Non-small Cell
Lung Cancer
Interventions
Drug: NK-102
First Posted Date
2025-07-08
Last Posted Date
2025-07-10
Lead Sponsor
University of California, Irvine
Target Recruit Count
9
Registration Number
NCT07053007
Locations
🇺🇸

Chao Family Comprehensive Cancer Center University of California, Irvine, Orange, California, United States

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News

FDA Approves First Liquid Embolic System for Hypervascular Tumor Treatment

The FDA has granted premarket approval to the Embrace Hydrogel Embolic System, marking the first liquid embolic specifically approved for hypervascular tumor embolization based on randomized controlled trial data.

Engineered Microglia: A Revolutionary Approach to Treating Alzheimer's Disease

UC Irvine researchers have developed a groundbreaking therapy using CRISPR-edited microglia that can detect and target amyloid plaques in Alzheimer's disease, delivering therapeutic proteins precisely where needed.

INSPIRE Trials: Computerized Alerts Improve Antibiotic Selection in Hospitalized Patients by Up to 35%

• NIH-funded clinical trials involving over 316,000 patients across 92 hospitals demonstrate that computerized alerts can improve appropriate antibiotic selection by 35% for abdominal infections and 28% for skin and soft tissue infections. • The INSPIRE trials used patient-specific data to identify individuals at low risk for antibiotic-resistant infections, prompting physicians to switch from broad-spectrum to standard antibiotics when appropriate. • Researchers from UC Irvine, Harvard Pilgrim Health Care Institute, and HCA Healthcare collaborated on the studies, which could significantly reduce antibiotic resistance and improve patient outcomes nationwide.

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