Multi-center Observational Study to Evaluate Epidemiology and Resistance Patterns of Common ICU-Infections (MOSER)

Completed

• Conditions: Nosocomial Infections
• Interventions: Other: No intervention

• Registration Number: NCT01346735
• Lead Sponsor: Indian Society of Critical Care Medicine

Brief Summary

Most literature on ICU infections and the resistant patterns comes from the western literature. This data may not truly reflect the incidence, epidemiology and resistance patterns in developing countries such as India. However, empiric antibiotic therapy is generally initiated using western guidelines. This can potentially lead to inadequate, inappropriate and ineffective empiric antibiotic therapy for ICU infections in the Indian setting. Hence in this multi-center observational study, we seek to:

1. To determine the incidence of ICU-related infections (VAP, CAUTI and CRBSI) in India

2. To explore the microbiology, resistance and treatment patterns of these infections

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-05-02
• Study First Submitted QC: 2011-05-02
• Study First Posted: 2011-05-03
• Study Start: 2011-08
• Primary Completion: 2012-10
• Study Completion: 2012-10
• Status Verified: 2016-08
• Last Update Submitted: 2016-08-30
• Last Update Posted: 2016-09-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 381

Inclusion Criteria

1. ICU stay >48 hours
2. One of the following infections (VAP, CAUTI or CRBSI)

Exclusion Criteria

1. Index ICU stay < 48 hours
2. Re-admissions to the ICU within the same hospitalization
3. Age >18 years or <70 years
4. Known HIV serology positivity
5. Burns
6. Solid organ or Bone-marrow transplant
7. No ICU-acquired infections (specifically VAP, CAUTI and CRBSI)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
ICU infections	No intervention	Infections acquired during the ICU stay

Trial Locations

Locations (1)

Indian Society of Critical Care Medicine; 🇮🇳 Mumbai, India