Roche Holding AG
- Country
- 🇨🇭Switzerland
- Ownership
- Public
- Established
- 1896-01-15
- Employees
- 103.6K
- Market Cap
- $270.5B
- Website
- http://www.roche.com
- Introduction
Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.
A Study to Explore Signs, Symptoms, and Biomarkers in Dry Eye Disease Participants Following Anti-inflammatory Treatment
- Conditions
- Dry Eye Disease
- Interventions
- Drug: Vevye®Drug: Xiidra®
- First Posted Date
- 2025-06-18
- Last Posted Date
- 2025-06-18
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 350
- Registration Number
- NCT07025811
A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease
- Conditions
- Von Willebrand Disease, Type 3
- Interventions
- Drug: von Willebrand Factor (VWF) ConcentratesDrug: Factor VIII (FVIII) ConcentratesDrug: von Willebrand Factor (VWF) and Factor VIII (FVIII) ConcentratesDrug: Bypassing Agents
- First Posted Date
- 2025-05-31
- Last Posted Date
- 2025-06-12
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 66
- Registration Number
- NCT06998524
- Locations
- 🇧🇪
UZ Leuven Gasthuisberg, Leuven, Belgium
A Study Investigating the Safety of RO7795081 and the Effect of RO7795081 on How the Body Processes Pitavastatin and Rosuvastatin in Otherwise Healthy Overweight or Obese Adult Participants
- Conditions
- OverweightObesity
- Interventions
- First Posted Date
- 2025-05-21
- Last Posted Date
- 2025-06-12
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 40
- Registration Number
- NCT06982131
- Locations
- 🇳🇱
PRA health sciences (ICON plc), Groningen, Groningen, Netherlands
Performance Study of the Cobas® BV/CV Test on Samples From Participants With and Without Symptoms of Bacterial Vaginosis and Candida Vaginitis
- Conditions
- Bacterial VaginosisCandida Vaginitis
- First Posted Date
- 2025-05-16
- Last Posted Date
- 2025-06-08
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 600
- Registration Number
- NCT06975436
- Locations
- 🇺🇸
Matrix Clinical Research, Los Angeles, California, United States
🇺🇸M3 Wake Research - San Diego at Convoy, San Diego, California, United States
🇺🇸Red Rocks OBGYN, Lakewood, Colorado, United States
A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity
- Conditions
- ObesityOverweightOverweight With One Weight Related Comorbidity
- Interventions
- First Posted Date
- 2025-05-11
- Last Posted Date
- 2025-05-29
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 234
- Registration Number
- NCT06965413
- Locations
- 🇺🇸
Pinnacle Research Group, Anniston, Alabama, United States
🇺🇸Encompass Clinical Research, Spring Valley, California, United States
🇺🇸K2 Medical Research South Orlando, LLC, Orlando, Florida, United States
A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
- Conditions
- Geographic AtrophyAge-related Macular Degeneration
- Interventions
- Drug: RO7669330Drug: Syfovre™Drug: Izervay™
- First Posted Date
- 2025-05-07
- Last Posted Date
- 2025-06-22
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 132
- Registration Number
- NCT06961370
- Locations
- 🇺🇸
Barnet Dulaney Perkins Eye Center, Sun City, Arizona, United States
🇺🇸Retina-Vitreous Associates Medical Group, Beverly Hills, California, United States
🇺🇸Retinal Consultants Medical Group Inc - Parkcenter Drive, Sacramento, California, United States
A Study Evaluating the Pharmacokinetics, Safety, and Efficacy of Cevostamab in Chinese Participants With Relapsed or Refractory Multiple Myeloma
- First Posted Date
- 2025-04-18
- Last Posted Date
- 2025-06-15
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 20
- Registration Number
- NCT06934044
- Locations
- 🇨🇳
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou City, China
🇨🇳Tianjin Institute of Hematology & Blood Diseases Hospital, Tianjin, Tianjin, China
A Study to Assess the Safety, Pharmacokinetics, and Activity of RO7790121 in Participants With Advanced MASH Liver Fibrosis
- First Posted Date
- 2025-03-30
- Last Posted Date
- 2025-06-15
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 50
- Registration Number
- NCT06903065
- Locations
- 🇺🇸
Adobe Clinical Research, LLC, Tucson, Arizona, United States
🇺🇸Gastrointestinal Specialists of Georgia, PC, Marietta, Georgia, United States
🇺🇸Delta Research Partners, LLC (Bastrop), Bastrop, Louisiana, United States
A Study Investigating the Effect of Different Approved Medications on How the Body Processes the Study Compound RO7795081
- Conditions
- Healthy Participants
- Interventions
- First Posted Date
- 2025-03-25
- Last Posted Date
- 2025-03-27
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 50
- Registration Number
- NCT06809608
- Locations
- 🇳🇱
ICON, Groningen, Netherlands
An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment
- Conditions
- Von Willebrand Disease, Type 3
- Interventions
- Drug: Von Willebrand Factor ConcentratesDrug: Von Willebrand Factor Concentrates and Factor VIII ConcentratesDrug: Factor VIII ConcentratesDrug: Recombinant Activated Factor VII
- First Posted Date
- 2025-03-19
- Last Posted Date
- 2025-05-29
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 40
- Registration Number
- NCT06883240
- Locations
- 🇧🇪
UZ Leuven Gasthuisberg, Leuven, Belgium
🇮🇹Universita' Degli Studi La Sapienza-Ist.Di Ematologia, Roma, Lazio, Italy
🇮🇹AOU Careggi, Firenze, Toscana, Italy