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Clinical Trials/NCT05900778
NCT05900778
Recruiting
Not Applicable

Implementation of a HABIT-ILE Intervention at William Lennox Neurological : a Randomized Controlled Trial

Université Catholique de Louvain3 sites in 1 country40 target enrollmentJune 10, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Acquired Brain Injury
Sponsor
Université Catholique de Louvain
Enrollment
40
Locations
3
Primary Endpoint
Flanker task
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

Using a randomized controlled trial design, in an hospital environment, possible changes induced by the "Hand-arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE)" treatment program will be investigated in functional activities of daily living, motor and cognitive assessment of children with acquired brain injury.

Detailed Description

The aim is to investigate, for the first time, the effectiveness of HABIT-ILE therapy in a hospital setting in the treatment of a population representative of the clinical population with children with acquired brain injuries. The hypothesis is that an in-hospital HABIT-ILE protocol will be more effective than conventional therapies usually given to children with acquired brain injury, and that this difference will be objectively demonstrated by clinical assessments of motor function, cognition and participation conducted before and after treatment periods. The aim of the study is therefore to evaluate the effect of intensive bimanual hand-arm therapy including the lower extremities (HABIT-ILE) on body functions and structures, activity and participation in children with acquired brain injury.

Registry
clinicaltrials.gov
Start Date
June 10, 2023
End Date
June 10, 2028
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Yannick Bleyenheuft

Professor

Université Catholique de Louvain

Eligibility Criteria

Inclusion Criteria

  • children with acquired brain injury of school
  • age 5 to 18 years inclusive

Exclusion Criteria

  • Unstable seizure
  • programmed botulinum toxin or orthopedic surgery in the 6 months previous to the intervention, during intervention period or 3months after the intervention time
  • Severe visual or cognitive impairments likely to interfere with intervention or testing session completion

Outcomes

Primary Outcomes

Flanker task

Time Frame: T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up)

Cognitive functions of the children will be assessed by Flanker task.

Changes in Gross Motor Function Measurement (GMFM 66)

Time Frame: T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up)

The GMFM has been developed to measure the change in gross motor function over time in children with cerebral palsy.

Secondary Outcomes

  • Changes in isometric muscular strength (Jamar)(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))
  • Stroop task(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))
  • Changes in unimanual dexterity: Box and Blocks test (BBT)(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))
  • Changes on bimanual function (Assisting Hand Assessment (AHA))(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))
  • Changes in 6 Minutes Walking Test (6MWT)(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))
  • Changes in Pediatric balance scale (PBS)(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))
  • Changes in Canadian Occupational Performance Measure (COPM)(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))
  • Changes in ACTIVLIM-CP questionnaire(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))
  • Changes in Pediatric Evaluation of Disability Inventory Computer Adaptive Test (PEDI-CAT)(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))
  • Changes in Pediatric quality of life inventory (PedsQL)(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))
  • Changes in Measure of Processes of Care (MPOC-20)(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))
  • Status in Wechsler Intelligence Scale for Children-Non verbal short version (WISC)(T0 (baseline))
  • Classification du niveau moteur: The Gross Motor Function Classification System - Expanded & Revised (GMFCS - E&R)(T0 (baseline))
  • QUALITY OF LIFE : KIDSCREEN 10(T0 (baseline), T1 (after 2weeks intervention), T2(3 months follow-up))

Study Sites (3)

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