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The effectiveness of cognitive behavioural therapy versus interpersonal psychotherapy in panic disorder with agoraphobia

Completed
Conditions
Panic disorder, agoraphobia
Mental and Behavioural Disorders
Registration Number
ISRCTN95465806
Lead Sponsor
Research Institute Experimental Psychopathology (EPP) (The Netherlands)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
92
Inclusion Criteria

1. Main diagnosis panic disorder with moderate/severe agoraphobia
2. Aged between 18 and 60

Exclusion Criteria

1. Co-morbid psychosis or bipolar disorder
2. The use of psychoactive drugs
3. Intelligence Quotient (IQ) less than 80
4. Insufficient knowledge of the Dutch language
5. Previous formal IPT or CBT received (for the same complaint in the past year)
6. Alcohol or drugs dependency
7. Cardiovascular disease
8. Respiratory disease
9. Epilepsy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Panic free status (defined with panic diaries) <br>2. Performance on a behavioural test (three situations) <br><br>Panic diaries are completed at zero months (pre-treatment), during treatment, three months (post treatment), four months (follow up one) and nine months (follow up two).<br><br>Performance on the behavioural test is assessed at zero months (pre-treatment), four months (follow up one) and nine months (follow up two).
Secondary Outcome Measures
NameTimeMethod
1. A composite measure of panic and agoraphobic measures (the Fear Questionnaire [FQ v+a], main phobia, Anxiety Sensitivity Index [ASI], Fear Of Fear [FOF], etc.,)<br>2. A composite measure of cognitive measures (e.g. Body Sensations Interpretation Questionnaire [BSIQ-14], Agoraphobic Cognitions Questionnaire [ACQ]) <br>3. An interpersonal measure (the Inventory of Interpersonal Problems [IIP]) <br>4. A composite measure of general psychopathology (the Symptom CheckList-90-R [SCL-90], State-Trait Anxiety Inventory [STAI]) <br><br>The outcomes are assessed at zero months (pre-treatment), three months (post treatment), four months (follow up one) and nine months (follow up two).
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