The Relationship Between Serum Endocan and ADMA Levels and Penile Doppler Ultrasonography in Erectile Dysfunction

Completed

• Conditions: Evaluation of the Relationship Between Serum Biomarkers (Endocan and ADMA) and Penile Doppler Ultrasonography Findings of Patients With Severe Erectile Dysf

• Registration Number: NCT05979467
• Lead Sponsor: Ankara Etlik City Hospital

Brief Summary

The gold standard diagnosis in patients admitted to the hospital with the complaint of erectile dysfunction is penile doppler ultrasonography. This procedure is an invasive procedure and can cause various complications. Therefore, in this study, we aimed to support and define the diagnosis of erectile dysfunction with some biomarkers that can be measured in blood samples. At this point, we performed penile doppler ultrasonography, which is the gold standard test, for all patients who applied with the complaint of erectile dysfunction, and compared the results of penile doppler and serum biomarkers in the patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-04-17
• Primary Completion: 2020-01-20
• Study Completion: 2020-06-12
• Status Verified: 2023-07
• Study First Submitted: 2023-07-28
• Study First Submitted QC: 2023-07-28
• Last Update Submitted: 2023-07-28
• Study First Posted: 2023-08-07
• Last Update Posted: 2023-08-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 73

Inclusion Criteria

• Patients with severe erectile dysfunction according to International Index of Erectile Function-15 questionnaire
• Patients who have not received medical or surgical treatment before
• Patients without comorbidity and related drug use

Exclusion Criteria

• Patients who have had previous pelvic trauma or surgery,
• Patients who have benefited from using phosphodiesterase-5 enzyme inhibitors,
• Patients with psychogenic erectile dysfunction and moderate or mild erectile dysfunction according to International Index of Erectile Function-15 questionnaire,
• Patients who have neurological disease, chronic liver disease and patients with chronic renal failure and those who used drugs that could cause erectile dysfunction

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the relationship between serum endocan (endothelial cell-specific molecule-1), ADMA (asymmetric dimethylarginine) values and penile Doppler ultrasonography findings in patients with severe Erectile dysfunction.	10 days from the outpatient clinic admission

Trial Locations

Locations (1)

Ankara City Hospital Bilkent; 🇹🇷 Ankara, Turkey