The Second COVID-19 Wave: Collateral Impact on Patients of Liver Disease

Completed

• Conditions: Liver Diseases
• Interventions: Other: This is an observational study

• Registration Number: NCT05167305
• Lead Sponsor: Institute of Liver and Biliary Sciences, India

Brief Summary

Hospital record of the patients of liver disease admitted from April-May 2021 and April-May 2019 will be reviewed. Patients will be analyzed and compared for the demographic characteristics, severity of liver disease at time of admission and outcome in form of survival or mortality, liver transplantation rates in the two time periods and the subsequent 30 d and 90 day readmission rate.

Monitoring and assessment: Hospital records of all patients of liver disease needing admission during the April-May 2019 and 2021, but without active COVID-19 infection, will be reviewed. Patients will be analyzed and compared for the demographic characteristics, severity of liver disease at time of admission and outcome in form of survival or mortality, liver transplantation rates in the two time periods and 30 d and 90 d readmission rate.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-12
• Study First Submitted: 2021-12-17
• Study First Submitted QC: 2021-12-21
• Study Start: 2021-12-22
• Study First Posted: 2021-12-22
• Primary Completion: 2021-12-31
• Study Completion: 2021-12-31
• Last Update Submitted: 2021-12-31
• Last Update Posted: 2022-01-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1316

Inclusion Criteria

1. Patients of liver disease requiring hospital admission

Exclusion Criteria

1. Active COVID-19 infection at time of admission or acquiring during hospital stay.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
liver disease without COVID-19 infection -April- May 2021	This is an observational study	-
liver disease without COVID-19 infection-April-May 2019	This is an observational study	-

Primary Outcome Measures

Name	Time	Method
Comparison of in-hospital mortality rate of patients of liver disease admitted in April-May 2021 and April-May 2019.	Until discharge or death

Secondary Outcome Measures

Name	Time	Method
Comparison of 31 to 90 days readmission rate of patients of liver disease.	Day 31-90
Comparison of 30 days readmission rate of patients of liver disease.	Day 30
Comparison of liver transplantation rates in the two time periods i.e., April-May 2021 and April-May 2019.	3 months

Trial Locations

Locations (1)

Institute of Liver & Biliary Sciences; 🇮🇳 New Delhi, Delhi, India