The impact of aerobic exercise habits on total serum bilirubin levels and their implications as a mediator of anti-atherosclerosis mechanisms
- Conditions
- annual health-checked participants
- Registration Number
- JPRN-UMIN000053207
- Lead Sponsor
- ihon University Hospital, Health Planning Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 10000
Not provided
We excluded 3,381 participants from the analysis according to the following criteria: unwillingness to provide informed consent for participation; positive history of ASCVD; leukocyte count more than 10000; C-reactive protein (CRP) level more than 3. 0 mg/dL; no record of frequency of fish consumption; presence of hepatitis B virus surface antigen, hepatitis C antibodies, liver cirrhosis, hepatocellular carcinoma, and metastatic liver cancer; or no measurement of white blood cell count, CRP levels, and TSB levels. We also excluded participants with TSB levels of more than 2.0 mg/dL to exclude constitutional jaundice as much as possible (i.e., the cut-off was to diagnose Gilbert syndrome in the absence of liver dysfunction). In addition, because there are cases in which TSB is higher in fasting blood samples than in random blood samples, we set the cut-off for TSB concentrations higher than the reference value
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparisons of participant characteristics, laboratory profiles, and lifestyle behaviors between participants with aerobic exercise habits and those without aerobic exercise habits
- Secondary Outcome Measures
Name Time Method Comparison of total serum bilirubin levels between participants with aerobic exercise habits or without aerobic exercise habits