BHCG Level in Day 4,7, in Comparison to Day 10 as an Indicator for Treatment Success

Phase 4

• Conditions: Ectopic Pregnancy
• Interventions: Drug: Methotrexate

• Registration Number: NCT01860690
• Lead Sponsor: Meir Medical Center

Brief Summary

The investigators want to compeer BHCG levels after Methotrexate ( MTX). treatment for Ectopic pregnancy in days 4 and 7 after MTX. to day 10 . The hypothesis is that "BHCG" level in day 10 is the best indicator for treatment success , superior to day 4 and 7 . According to the investigators impression BHCG level rises in days 4 and 7 due to destruction of the trophoblast tissue , and only day 10 is an indicator for treatment success

Detailed Description

Not available

Study Timeline

• Study Start: 2011-11
• Study First Submitted: 2012-11-20
• Status Verified: 2012-12
• Study First Submitted QC: 2013-05-22
• Last Update Submitted: 2013-05-22
• Study First Posted: 2013-05-23
• Last Update Posted: 2013-05-23
• Primary Completion: 2013-11
• Study Completion: 2014-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• patients with ectopic pregnancy
• healthy
• hemodynamic stable
• first ectopic

Exclusion Criteria

• hemodynamic non-stable
• abnormal liver or kidney function
• allergy reaction to MTX

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
MTX , treatment outcome	Methotrexate	patient receiving MTX. in a dosage of 50 mg/m\^2 , IM , in single dose

Primary Outcome Measures

Name	Time	Method
To measure the change of levels of "BHCG" in patients receiving Methotrexate for treatment of ectopic pregnancy in days 4, 7, and 10 post treatment	the change of levels in days 4, 7, and 10 post MTX injection	To compeer levels of BHCG in days 4 and 7 to day 10 after injection of MTX. for Ectopic pregnancy treatment

Trial Locations

Locations (1)

Dr. Zvi Klein; 🇮🇱 Kefar-saba, Israel