Influence of milk as compared to soy phospholipids on risk factors for cardiovascular disease

Not Applicable

• Conditions: E78.9; Disorder of lipoprotein metabolism, unspecified

• Registration Number: DRKS00003125
• Lead Sponsor: Max Rubner-Institut Bundesforschungsinstitut für Ernährung und Lebensmittel

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-06-09
• Study Completion: 2011-06-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Male
• Target Recruitment: 58

Inclusion Criteria

Overweight male volunteers, age 50- 76 years, non-smokers; written informed consent

Exclusion Criteria

- fasting glucose levels >120 mg/dl
- Known metabolic or gastro-intestinal diseases, which affect the absorption, metabolism or excretion of food or food components;
- Known allergy against milk or soy components
- intake of supplements which might affect the parameters tested
- intake of drugs which might affect the parameters tested
- intestinal tract surgery or corticoid steroid treatment within the last 3 months
- Inability to understand and to comply with the study protocol;
- unusually high consumption of milk or dairy products
- occurrence of acute gastrointestinal disorders during intervention
- Occurrence of other unexpected events with relevance for the study outcome
- withdrawal of consent to participate

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ratio of total zu HDL-cholesterol in serum (after 7 weeks)

Secondary Outcome Measures

Name	Time	Method
Further parameters of lipid metabolism(triglycerides, LDL-cholesterol), glucose metabolism (glucose, insulin), hepatic metabolism (GOT, GGT, GPT), thiol metabolism (glutathione, homocysteine), inflammation (CRP, endothelial adhesion molecules) and body composition after 7 weeks intervention