Gastrectomy Plus Prophylactic Cholecystectomy in Gastric Cancer Surgery
- Conditions
- Gastric Cancer
- Interventions
- Procedure: cholecystectomy
- Registration Number
- NCT00757640
- Lead Sponsor
- Italian Research Group for Gastric Cancer
- Brief Summary
The patients will be divided into two groups: in the first group the patient will be submitted to prophylactic cholecystectomy during standard surgery for curable gastric cancer (subtotal or total gastrectomy), while in the second group will be submitted to standard gastric surgery only.
- Detailed Description
The incidence of gallstones and gallbladder sludge is known to be higher in patients after gastrectomy than in general population. This higher incidence is probably related to surgical dissection of the vagus nerve branches and the anatomical gastrointestinal reconstruction. Therefore, some surgeons perform routine concomitant cholecystectomy during standard surgery for gastric malignancies. However, not all the patients who are diagnosed to have cholelithiasis after gastric cancer surgery will develop symptoms or require additional surgical treatments and a standard laparoscopic cholecystectomy is feasible even in those patients who underwent previous gastric surgery.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 150
- Patients undergoing standard gastric surgery for cancer
- gallbladder disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description A cholecystectomy cholecystectomy
- Primary Outcome Measures
Name Time Method Reduced biliary complications 5 years
- Secondary Outcome Measures
Name Time Method Improved quality of life 5 years
Trial Locations
- Locations (1)
Azienda Ospedaliero-Universitaria Careggi - Chirurgia Generale ed Oncologica
🇮🇹Florence, Italy