Does mothers fat tissue send messages to the baby?
Not Applicable
- Conditions
- Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2019/08/020505
- Lead Sponsor
- ational Institute of Health NIH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Pregnant women with gestational diabetes and pregnant women with normal glucose tolerance
Exclusion Criteria
-
Pregnant women with Type 1 or Type 2 diabetes,
Hemoglobin less than 9,
IVF conception,
other pregnancy complications
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Associations between: 1.maternal and cord blood adipocyte-derived (ADEmiRNA) exosomal microRNAs that target adipogenesis <br/ ><br>2. With infant adiposityTimepoint: 1. Exosome extraction: 9 months from start of study <br/ ><br>2. miRNA profiling: 3 months after outcome of step 1 <br/ ><br>3. miRNA data analysis: 8 months
- Secondary Outcome Measures
Name Time Method Association of ADEmiRNA expression with intrauterine exposures (i.e. glycemia and vitamin B12 status during pregnancy)Timepoint: Same as primary outcome