HDR Curve for Heparin Dose Determination in pediatric patients undergoing cardiac surgery
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/08/072588
- Lead Sponsor
- AIIMS NEW DELHI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Pediatric cardiac surgical patients less than 14 years old posted for elective cardiac surgery on cardiopulmonary bypass.
Exclusion Criteria
Patients who refuse to participate in the study
Emergency surgery
Redo surgery
Patients with allergy to Heparin or Protamine
Renal dysfunction
Severe liver disease
CPB time more than 180 minutes
Patients on preoperative anticoagulants
Patients greater than 14 years of age
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To ascertain whether or not heparin dose administered as determined by HDR curve achieves target ACT of 480 before CPB.Timepoint: Before going on bypass.
- Secondary Outcome Measures
Name Time Method To compare total dose of heparin given in both the groups. <br/ ><br>To compare protamine dose administered in both the groups. <br/ ><br>To compare amount of postoperative blood loss between the study groups. <br/ ><br>Timepoint: Intraoperative and post operative