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SWOG-9208 Quality of Life and Health Status in Patients With Stage I or Stage II Hodgkin's Disease

Completed
Conditions
Lymphoma
Psychosocial Effects of Cancer and Its Treatment
Registration Number
NCT00002563
Lead Sponsor
SWOG Cancer Research Network
Brief Summary

RATIONALE: Quality-of-life assessment in patients undergoing cancer treatment may help determine the intermediate- and long-term effects of treatment on patients with cancer.

PURPOSE: This clinical trial studies the impact of therapy on the health status and quality of life of patients with stage I or stage II Hodgkin's disease who are receiving radiation therapy with or without chemotherapy.

Detailed Description

OBJECTIVES: I. Evaluate prospectively the health status and quality of life of patients with Stage I/IIA Hodgkin's disease randomized on protocol SWOG-9133 (CLB-9391) to treatment with subtotal nodal irradiation with vs. without 3 courses of doxorubicin/vinblastine. II. Describe the short-term effects of these treatments on these patients and compare their impact on quality of life (i.e., patient symptom status, health status, fatigue). III. Evaluate the intermediate and long-term effects of these treatments on these patients and compare their impact on quality-of-life outcomes over 5 years.

OUTLINE: Quality-of-Life Assessment. Cancer Rehabilitation Evaluation System Short Form, CARES-SF; Symptom and Personal Information Questionnaire (including Symptom Distress Scale, MOS SF-36 Fatigue Scale, MOS SF-36 Health Perception Rating, Demographics); Cover Sheet.

PROJECTED ACCRUAL: Approximately 500 patients will be accrued over 7 years.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
263
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (11)

University of Massachusetts Memorial Medical Center

🇺🇸

Worcester, Massachusetts, United States

State University of New York - Upstate Medical University

🇺🇸

Syracuse, New York, United States

Walter Reed Army Medical Center

🇺🇸

Washington, District of Columbia, United States

Ellis Fischel Cancer Center - Columbia

🇺🇸

Columbia, Missouri, United States

Barnes-Jewish Hospital

🇺🇸

Saint Louis, Missouri, United States

Roswell Park Cancer Institute

🇺🇸

Buffalo, New York, United States

Comprehensive Cancer Center of Wake Forest University Baptist Medical Center

🇺🇸

Winston-Salem, North Carolina, United States

University of Tennessee, Memphis Cancer Center

🇺🇸

Memphis, Tennessee, United States

Beth Israel Medical Center

🇺🇸

New York, New York, United States

University of Iowa Hospitals and Clinics

🇺🇸

Iowa City, Iowa, United States

Rhode Island Hospital

🇺🇸

Providence, Rhode Island, United States

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