Intraoperative Brain Microdialysis to Assess Neuroinflammation in Epileptic Tissue Immediately Prior to Surgical Resection.
Not Applicable
- Conditions
- Epilepsy
- Registration Number
- NCT04531722
- Lead Sponsor
- Mayo Clinic
- Brief Summary
This research study will investigate the fluid from the area of the brain that is being removed during clinical epilepsy surgery. The goal is to analyze this fluid for inflammatory markers that can potentially help identify new strategies in the future to control seizures in individuals with epilepsy who fail to respond to currently available drugs.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 3
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Detection of analytes/protein Through study completion, up to 5 years Presence of protein in the microdialysate
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What inflammatory markers are analyzed in intraoperative brain microdialysis for epilepsy surgery outcomes?
How does neuroinflammation in epileptic tissue correlate with seizure frequency and drug resistance mechanisms?
What are the comparative efficacy and safety profiles of intraoperative microdialysis versus standard-of-care seizure monitoring techniques?
Which biomarkers identified through brain microdialysis could guide personalized anti-inflammatory therapies for drug-resistant epilepsy?
What molecular pathways are associated with neuroinflammation in focal cortical dysplasia and tuberous sclerosis-related epilepsy?
Trial Locations
- Locations (1)
Mayo Clinic in Rochester
🇺🇸Rochester, Minnesota, United States
Mayo Clinic in Rochester🇺🇸Rochester, Minnesota, United States