To estimate and compare a biomarker in saliva in gum disease patients with and without diabetes before and after treatment.
Phase 1
Completed
- Conditions
- Health Condition 1: null- Chronic Periodontitis With And Without Diabetes MellitusHealth Condition 2: E118- Type 2 diabetes mellitus with unspecified complications
- Registration Number
- CTRI/2018/03/012649
- Lead Sponsor
- Meharunneesa Nallakkendavida
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
1.Subjects age ranging from 35-55 years.
2.Subjects with minimum complement of 20 teeth.
3.Subjects who are diagnosed with chronic periodontitis with at least two non-adjacent sites with probing pocket depth (PPD/CAL) of >= to 5mm.
4.Subjects who are diagnosed with diabetes with random blood sugar (RBS) values (>=180mg/dl).
Exclusion Criteria
1.Subjects who had undergone any periodontal treatment in the past 6 months.
2.Subjects who are smokers.
3.Subjects who have received antibiotics/ anti-inflammatory drugs/ steroids in past 6 months.
4.Pregnant and lactating women.
5.Subjects with history of cardiac diseases, malignancy or any other inflammatory disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sialic acid level will be decreased in chronic periodontitis patients with and without diabetes after scaling and root planingTimepoint: 30,60 .90 days
- Secondary Outcome Measures
Name Time Method Reduction in inflammation and patient comfortTimepoint: 30 ,60 .90 days