Comparison of Salivary Alkaline Phosphatase levels during single step vs two step Twin Block in growing childre
Phase 4
- Conditions
- Health Condition 1: R930- Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
- Registration Number
- CTRI/2024/04/066030
- Lead Sponsor
- Dr Priyanka Badu
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Clinically
No previous history of any orthodontic treatment.
Each subject with a full cusp class II relationship bilaterally with convex facial profile.
The overjet should be more than than 7 mm.
VTO improved with anterior positioning of mandible.
Radiographically:
ANB angle more than 4 degrees with favourable growth pattern.
Subjects who are at accelerated phase of pubertal growth spurt (CVMI stage-3), MP3-FG and MP3- G stage.
Exclusion Criteria
Syndromic cases.
Children with following disorders –
A) Disorders of Bone metabolism.
B) Hepatobiliary disorders.
C) Systemic Inflammatory diseases.
Children with compromised oral hygiene.
Children taking drugs that can alter salivary flow.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To Assess and compare the levels of salivary alkaline phosphatase during single step vs two step advancement of mandible using twin block in growing skeletal class II children.Timepoint: Baseline salivary ALP levels prior to twin block delivery, 1 month, 2months, 3 months, 4 months, 5 months, 6 months
- Secondary Outcome Measures
Name Time Method 1.Assess and compare skeletal and dentoalveolar effects of twin block therapy with a single step vs two step mandibular advancement. <br/ ><br>2. Correlation of salivary alkaline phosphatase levels with skeletal effects. <br/ ><br>Timepoint: Every month for 6 months