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How salivary alkaline phosphatase levels change during growth modulation therapy by twin block in growing skeletal class II children?

Not Applicable
Conditions
Health Condition 1: K118- Other diseases of salivary glands
Registration Number
CTRI/2021/05/033760
Lead Sponsor
Dipak Khade
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. skeletal class II malocclusion due to mandibular retrognathism.

2. No previous history of any orthodontic treatment.

3. Each subject with a full cusp class II or end-on molar relationship bilaterally with convex facial profile.

4. The overjet should be more than than 4 mm.

5. VTO improved with anterior positioning of mandible.

Exclusion Criteria

1.Syndromic cases.

2.Children with following disorders â??

A) Disorders of Bone metabolism.

B) Hepatobiliary disorders.

C) Systemic Inflammatory diseases.

3.Children with compromised oral hygiene.

4.Children taking drugs that can alter salivary flow.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Monthly assessment of salivary alkaline phosphatase levels during growth modulation therapy by twin block in growing skeletal class II children.Timepoint: Base line and then after 1,2,3,4,5 and 6 months ( monthly intervals upto 6 months )
Secondary Outcome Measures
NameTimeMethod
1.Assessment of skeletal and dentoalveolar effects of growth modulation treatment by twin block. <br/ ><br>2.Correlation of salivary alkaline phosphatase levels with skeletal effects. <br/ ><br>Timepoint: 6 months
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