Comparison of the efficacy, tolerance and cost of Algostéril vs Negative Pressure Therapy in preparation for skin grafting following surgical excisio

Not Applicable

Completed

• Conditions: Surgical removal with a granulation phase before a skin graft supported in restorative, reconstructive and plastic surgery service; Surgery; Skin graft

• Registration Number: ISRCTN60292377
• Lead Sponsor: aboratoires Brothier

Brief Summary

2020 Results article in https://pubmed.ncbi.nlm.nih.gov/32537348/ (added 08/03/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-02-23
• Study Completion: 2016-09-10
• Last Update Posted: 20 March 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 95

Inclusion Criteria

1. Written informed consent
2. Patients aged 18 years or older
3. Scheduled for surgical removal with a granulation phase before a skin graft

Exclusion Criteria

1. Uncontrolled hyperglycemia
2. Excision is secondary to burns
3. Treated within 30 days before enrollment with immunosuppressants, chemotherapy, radiotherapy on the site excised,

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time to optimal granulation. After excision, evaluation for grafting every 7 days and until the wound can receive skin graft.

Secondary Outcome Measures

Name	Time	Method
<br> 1. Care costs: at each dressing change<br> 2. Patient quality of life: every 7 days and until the wound can receive skin graft.<br> 3. Tolerance: thought the trial<br>