Efficacy of chlorhexidine in the first week after an oral biopsy
- Conditions
- Patients who need to perform an oral biopsy due to different oral conditions.Oral Health
- Registration Number
- ISRCTN14440167
- Lead Sponsor
- niversity of Turin
- Brief Summary
2020 results in https://www.ncbi.nlm.nih.gov/pubmed/32161233 (added 09/04/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 354
1. Consecutive caucasian patients, attending the Oral Medicine Section of the Department of Surgical Sciences, Turin Hospital
2. Patients are those normally referred for histological determination of oral lesions
3. Adults aged 18 and older
1. Clinically significant medical history (e.g. systemic infective disease, heart and vascular disease, liver disease, haematological disease, deficiency of the coagulation, diabetes and neoplastic disease)
2. Immunosuppressed or immunocompromised or those who received radiotherapy to the head and neck area
3. Already under antibiotic treatment for any other reasons or treated or under treatment with intravenous amino-bisphosphonates
4. Pregnant or lactating females; patients with incapacity to understand verbal and written instructions
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. Quality of life is detailed by the patients using the Italian version of the oral health related quality of life questionnaire measured by the Oral Health Impact Profile-14 (OHIP-14) at day six<br> 2. Post-operative pain is detailed by the patients using a Visual Analogue Scale (VAS) at baseline, day one, three, and six<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Early post-operative complications are detailed during the clinical evaluation at day seven<br> 2. Healing of biopsy site is measured during the clinical evaluation at day seven<br>