Arterial Blood Gases in Weaning of Mechanical VEntilation
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Type of spontaneous breathing trial performed
研究概览
简要总结
Weaning of mechanical ventilation is an important phase of ICU (Intensive Care Unit) patient hospitalization. Patients have to pass a spontaneous breathing trial, can have a phase of pause with mechanical ventilation before extubation and then can be weaned of invasive mechanical ventilation. Spontaneous breathing trial can be performed with a T-Tube or with Pressure support without PEEP (End Expiratory Positive Pressure) . Duration of spontaneous breathing trial range from 30 minutes to 120 minutes. Some clinicians performed an arterial blood gases at the end of the spontaneous breathing trial but this practice is not really defined and clearly explained in recommendations. Patients can benefit of ventilation support after extubation like non invasive pressure support or high flow nasal canulae. The procedure can be very different from a center to another, especially for arterial blood gases at the end of spontaneous breathing trial. Our aim is to observe in a multicenter study the daily practice of weaning of mechanical ventilation especially for arterial blood gases.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Older than 18 years
- •first attempt of weaning of mechanical ventilation
排除标准
- •withholding of life sustaining therapies
- •spontaneous breathing trial unsuccessful
结局指标
主要结局
Type of spontaneous breathing trial performed
时间窗: In the 24 hours of spontaneous breathing trial
Spontaneous breathing trial is performed either with pressure support or with a T-Piece
次要结局
- Death(The first 28 days following extubation)
- Arterial blood gases at the end of spontaneous breathing trial(In the hour of spontaneous breathing trial)
- Duration of spontaneous breathing trial(The day of the spontaneous breathing trial)
- Need for reintubation(During the seven days following extubation)
- Etiology of reintubation(During the seven days following extubation)
- Ventilator associated pneumoniae(From 48 hours after extubation until extubation)
- Ventilatory procedure at the end of spontaneous breathing trial: either immediate extubation or pressure support ventilation with intubation(The day of extubation if extubation performed)
- Frequency and type of ventilatory support after extubation(The day of extubation if extubation performed)
- days alive without mechanical ventilation(during the first 28 days of intensive care hospitalization.)