Arterial Blood Gases in Weaning of Mechanical VEntilation
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Weaning of Mechanical Ventilation
- Sponsor
- Centre Hospitalier Universitaire de Besancon
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Type of spontaneous breathing trial performed
- Status
- Active, Not Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
Weaning of mechanical ventilation is an important phase of ICU (Intensive Care Unit) patient hospitalization. Patients have to pass a spontaneous breathing trial, can have a phase of pause with mechanical ventilation before extubation and then can be weaned of invasive mechanical ventilation. Spontaneous breathing trial can be performed with a T-Tube or with Pressure support without PEEP (End Expiratory Positive Pressure) . Duration of spontaneous breathing trial range from 30 minutes to 120 minutes. Some clinicians performed an arterial blood gases at the end of the spontaneous breathing trial but this practice is not really defined and clearly explained in recommendations. Patients can benefit of ventilation support after extubation like non invasive pressure support or high flow nasal canulae. The procedure can be very different from a center to another, especially for arterial blood gases at the end of spontaneous breathing trial. Our aim is to observe in a multicenter study the daily practice of weaning of mechanical ventilation especially for arterial blood gases.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Older than 18 years
- •first attempt of weaning of mechanical ventilation
Exclusion Criteria
- •withholding of life sustaining therapies
- •spontaneous breathing trial unsuccessful
Outcomes
Primary Outcomes
Type of spontaneous breathing trial performed
Time Frame: In the 24 hours of spontaneous breathing trial
Spontaneous breathing trial is performed either with pressure support or with a T-Piece
Secondary Outcomes
- Death(The first 28 days following extubation)
- Arterial blood gases at the end of spontaneous breathing trial(In the hour of spontaneous breathing trial)
- Duration of spontaneous breathing trial(The day of the spontaneous breathing trial)
- Need for reintubation(During the seven days following extubation)
- Etiology of reintubation(During the seven days following extubation)
- Ventilator associated pneumoniae(From 48 hours after extubation until extubation)
- Ventilatory procedure at the end of spontaneous breathing trial: either immediate extubation or pressure support ventilation with intubation(The day of extubation if extubation performed)
- Frequency and type of ventilatory support after extubation(The day of extubation if extubation performed)
- days alive without mechanical ventilation(during the first 28 days of intensive care hospitalization.)