Non Invasive Mechanical Ventilation VERSUS Oxygen MASK After Successful Weaning From Invasive Mechanical Ventilation in Pediatrics
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Assiut University
- Enrollment
- 104
- Primary Endpoint
- risk of respiratory failure after non invasive ventilation use
Study Overview
Brief Summary
Conventional mechanical ventilation is a core feature of intensive care. Weaning and removal of endotracheal tube are crucial processes, which often account for a considerable part of Conventional mechanical ventilation total time. Unsuccessful extubation has been noted to be associated with an increase of both morbidity and mortality in adult and pediatric patients
Detailed Description
The documented rate of failed extubations ranges from 4.1 to 14% in pediatric intensive care units.Therefore, strategies preventing the need for reintubation are needed.
Non invasive ventilation has been proposed as useful therapy to wean patients after unsuccessful weaning trials and to avoid reintubation in adults, though controversy exists at this concern.
This technique is increasingly being used in pediatric patients over the last years. The objective of the present study was to determine post extubation Non invasive ventilation characteristics and to identify risk factors of post extubation Non invasive ventilation failure in children
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Supportive Care
- Masking
- None
Eligibility Criteria
- Ages
- 1 Month to 18 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •all the patients with successful weaning from invasive mechanical ventilation
Exclusion Criteria
- •Maxillofacial trauma
- •Gastrointestinal obstruction
- •Severe lung secretion
- •Irreversible organ failure
Arms & Interventions
oxygen mask control group
patients will receive oxygen by mask will be monitored regarding oxygen saturation, blood pressure, respiratory rate, heart rate, arterial blood gases
Intervention: oxygen mask (Device)
non invasive ventilation study group
patients will receive non invasive ventilation after successful weaning from invasive ventilation and will be monitored regarding oxygen saturation, blood pressure, respiratory rate, heart rate, arterial blood gases
Intervention: non invasive mechanical ventilation in pediatrics (Device)
Outcomes
Primary Outcomes
risk of respiratory failure after non invasive ventilation use
Time Frame: one week after successful weaning from invasive mechanical ventilation
The patients will be evaluated to determine any manifestation of respiratory failure
Secondary Outcomes
- complications of non invasive mechanical ventilation in pediatrics(one week after use of non invasive ventilation)
- length of hospital stay after non invasive ventilation use(one month after use of non invasive ventilation)
Investigators
Mohamed Khalaf
principal investigator
Assiut University