Clinical Application and Outcome of Non-invasive Ventilation in Different Chest Diseases
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- percentage of patients need mechanical ventilation
研究概览
简要总结
Noninvasive ventilation is increasingly used method of respiratory management in both the emergency room and critical care. Noninvasive ventilation delivers mechanically assisted breaths without the placement of an artificial airway and has become an important mechanism of ventilator support inside and outside the intensive care unit.
Noninvasive ventilation is further subdivided into negative pressure ventilation which is the iron lung, first used in 1928 and the Hayek oscillator, is a more recently designed to provide negative pressure during inspiration and positive pressure during expiration. Noninvasive positive pressure ventilation can be used as continuous positive airway pressure or bi-level positive airway pressure.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •obstructive sleep apnea syndrome
- •acute exacerbation Chronic obstructive pulmonary disease
- •pneumonia
- •interstitial lung diseases
排除标准
- •Patients refuse Non invasive ventilation
- •Patients with absolute indication for Mechanical ventilator (in respiratory arrest or unstable cardiorespiratory status, trauma or burns involving the face, or gastric surgery, reduced consciousness, Pneumothorax
- •Patients with contraindication to Non invasive ventilation
结局指标
主要结局
percentage of patients need mechanical ventilation
时间窗: 1-48 hours
the number of patients without improvement on non-invasive ventilator and require transfer to mechanical ventilator
次要结局
未报告次要终点
研究者
Ahmed Mohamed Abbas
principal investigator
Assiut University