Subcutaneous oxytocin administration before a surgical incision to reduce pai
Phase 1
Completed
- Conditions
- aparascopic surgery, hemodynamic nociceptive automatic response and post-surgical painSurgeryLaparascopic surgery, hemodynamic nociceptive automatic response and post-surgical pain
- Registration Number
- ISRCTN29008609
- Lead Sponsor
- Instituto de Neurobiología. UNAM. lab. B16. Dr. Miguel Condés-Lara
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
1. Aged 18-75
2. ASA (American Society of Anesthesiologists) Hazard Scale I or ASA II
3. Undergoing scheduled laparoscopic surgery
Exclusion Criteria
1. ASA III or more
2. Emergency surgery
3. Hemodynamic instability
4. Surgical complications (bleeding, intestinal injury)
5. Taking inotropic drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. Nociceptive hemodynamic response to surgical incision recorded as the change in the heart rate, diastolic and systolic blood pressure, measured using a GCE Healthcare model Datex Ohmeda S5 monitor during the surgical procedure<br> 2. Post-surgical pain level, assessed using a visual analogue scale (VAS) at the post-anesthetic care unit arrival, post-anesthetic care unit discharge and during hospitalisation<br>
- Secondary Outcome Measures
Name Time Method <br> Incidence of adverse effects and side effects, monitored throughout the study and additionally assessed by a post-operative evaluatiob by the surgeon 7-10 days after surgery<br>