Impact of intravenous oxytocin on lung haemodynamics and gas exchange during caesarean section under general and spinal anaesthesia

Not Applicable

Completed

• Conditions: oxygen saturation during caesarean section under general and spinal anaesthesia; Anaesthesiology - Anaesthetics; Reproductive Health and Childbirth - Childbirth and postnatal care

• Registration Number: ACTRN12616000166471
• Lead Sponsor: Obstetrics and Gynecology Clinic, Clinical Hospital Center Zagreb

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-02-10
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 70

Inclusion Criteria

Patients scheduled for elective caesarean section

Exclusion Criteria

Patients receiving standard doses of oxytocin (5 IU as a bolus plus 5 IU in infusion through 3 minutes) and patients receiving larger doses of oxytocin (>20 IU intraoperatively).
Underlying lung disease (asthma, COPD)
Preeclampsia, hypertension
Intraoperative blood loss above 800 ml

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
changes in oxygen saturation after apllication of intravenous oxytocin by pulse oximetry[Period after intravenous application of oxytocin until the end of the surgical procedure (caesarean section)]

Secondary Outcome Measures

Name	Time	Method
changes in mean arterial pressure (MAP) by non-invasive blood presurre and pulse by pulse oximetry after intravenous application of oxytocin[period after intravenous application of oxytocin until the end of the surgical procedure (caesarean section)]