Clinical Effects of Delgocitinib Ointment on Skin Barrier Dysfunction in Pediatric Atopic Dermatitis
Not Applicable
Recruiting
- Conditions
- Atopic Dermatitis
- Registration Number
- JPRN-UMIN000049841
- Lead Sponsor
- ational Hospital Organization Sagamihara National Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Patients with a history of use of group II or higher topical steroids or delgocitinib ointment on the forearm within 1 month (2) Patients with signs of infection on the forearm (3) Patients with a history of use of biological drugs within 1 year or who are going to use biological drugs during participation in the study (4) Other patients deemed inappropriate as research subjects by the principal investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in TEWL and SCH from baseline to 12 weeks
- Secondary Outcome Measures
Name Time Method Change in TARC, SCCA2, EASI, pEASI and vIGA from baseline to 12 weeks TEWL, SCH, and questionnaire scores for eczematous and non-eczematous areas at 12 weeks TARC, SCCA2, EASI, pEASI and vIGA at 12 weeks EIS results at baseline and at 12 weeks, and findings from tape stripping