Efficacy of Intramuscular Naloxone 0.4mg. in Prophylaxis of Intrathecal Morphine Induced Pruritus After Cesarean Section

Not Applicable

Completed

• Conditions: Morphine Adverse Reaction
• Interventions: Drug: normal saline; Drug: naloxone

• Registration Number: NCT00890942
• Lead Sponsor: Mahidol University

Brief Summary

The purpose of this study is to determine whether intramuscular naloxone 0.4mg. is effective in prophylaxis of intrathecal morphine induced pruritus after cesarean section.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2009-04-26
• Study First Submitted QC: 2009-04-29
• Study First Posted: 2009-04-30
• Study Start: 2009-05
• Primary Completion: 2009-10
• Study Completion: 2010-05
• Status Verified: 2011-07
• Last Update Submitted: 2011-07-22
• Last Update Posted: 2011-07-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• patient schedule for cesarean section ASA class 1

Exclusion Criteria

• have contraindication for spinal block
• complicated pregnancy
• have history of drug abuse during pregnancy
• obesity BMI>35kg./m2

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
normal saline	normal saline	-
naloxone	naloxone	-

Primary Outcome Measures

Name	Time	Method
efficacy of intrathecal naloxone 0.4mg. in prophylaxis of intrathecal morphine induced pruritus after cesarean section	24 hour

Trial Locations

Locations (1)

Anesthesiology department, Siriraj Hospital, Mahidol University; 🇹🇭 Bangkok, Thailand