Validation of a new PCO2 measurement catheter
Completed
- Conditions
- splanchnic ischemia10018031
- Registration Number
- NL-OMON34918
- Lead Sponsor
- Medisch Spectrum Twente
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
patienst referred for potential gastrointestinal ischemia (postprandial pain, weight loss or diarrhea, otherwise unexplained, or associated with vascular stenoses)
Exclusion Criteria
Age < 18 years,
Poor clinical condition which would make the diagnosis of GI ischemia clinically unimportant.
End-stage liver disease
End-stage cardiopulmonary disease.
Hemorrhagic disorders
Severe esophageal inflammation
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Air tonometry: a. precision and bias of PCO2 measurement<br /><br>Fluid tonometry: a. correction factors for 10, 20, and 30 minutes<br /><br>equilibration time, b. precision and bias calculation for each dwell time<br /><br>Patient study: measurement errors with use of the tonocap in patients </p><br>
- Secondary Outcome Measures
Name Time Method <p>1.Blood gas analyser: correction factor for PCO2 measurement from saline.<br /><br>2.Patient study:<br /><br>a.The handling characteristics for placement in the small bowel<br /><br>b.time needed for small bowel placement during fluoroscopy<br /><br>c.handling characteristics during 24 hour measurement<br /><br>d.patient (in)convenience during 24 hour measurement</p><br>