ROLE OF INDIVIDUALIZED HOMOEOPATHIC MEDICINE IN TREATING THE SYMPTOMS OF ENDOMETRIOSIS

Phase 2

Recruiting

Conditions: Endometriosis,

Registration Number: CTRI/2021/04/032599

Lead Sponsor: National Institue of Homoeopathy

Brief Summary: Endometriosis is a condition where tissue similar to the lining of the uterus (the endometrial stroma and glands, which should only be located inside the uterus) is found elsewhere in the body. Endometriosis is an estrogen dependent disease thus usually effects women of reproductive age group, having 20-50% prevalence in infertile women but it can be as high as 71-87% in women with chronic pelvic pain. Homoeopathic literature has given generous attention to female heath issues & endometriosis though not directly mentioned in the texts, is being incorporated through the description of various manifesting symptoms relating to the menstrual state and thus individualized homoeopathic medicines plays a considerable role in treating endometriosis. Mintonâ€™s Uterine Therapeutics is a Regional Clinical Repertory which serves as a useful monograph on the problems of menstruation & other related functions. An open non-randomized single arm prospective clinical study is being taken up at the OPD of National Institute of Homoeopathy, Kolkata. West Bengal. 40 patients presenting with symptoms of Endometriosis with a positive finding in either USG/TVS and/Laparoscopy will be taken for the study. Outcome data will be assessed primarily through symptoms using Numeric Rating Scale (recorded at baseline and then every 4 weeks for 6 months) & RAND Item 36 Health Survey 1.0 (recorded at baseline and at 6 months). Changes in the outcome will be tested at baseline and at 6 months by statistical tests as appropriate. An attempt will be made to show changes in the pathology through lab investigations - USG/TVS and/Laparoscopy as a secondary outcome measure.

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: Female

Target Recruitment: 40

Inclusion Criteria

1.Female patient with a positive diagnostic finding for Endometriosis.
2.Reproductive age group (18-45 years) 3.Patients willing to give consent for participating in the study.
4.Patients who can read Bengali and/ Hindi and/English.

Exclusion Criteria

1.Pregnant women or lactating mothers.
2.Diagnosed cases of unstable psychiatric illness or other systemic disease affecting quality of life or some life threatening illness.
3.Patients not willing to participate in the study.
4.Substance abuse and/or dependence.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Numeric Rating Scale	Baseline and six months
2. RAND Item 36 Health Survey 1.0 Questionnaire	Baseline and six months

Secondary Outcome Measures

Name	Time	Method
An attempt will be made to show changes in the pathology through lab investigations- USG/TVS and/laparoscopy	baseline to six months

Trial Locations

Locations (1): National Institute of Homoeopathy
🇮🇳
Parganas, WEST BENGAL, India
National Institute of Homoeopathy
🇮🇳Parganas, WEST BENGAL, India
Arpita Sen
Principal investigator
8837357872
drarpitasen666@gmail.com