Effectiveness of autologous platelet rich plasma for the treatment of pressure ulcers in people with spinal cord injury: a randomized controlled trial.

Indian Council of Medical Research0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1. Participants with age more than 18 and less than 65 years.
•2. Participants or close relative must be able to give voluntary written consent.
•3. Participants with sacral PU with <3m duration.
•4. Pressure ulcer of grade III & IV will be included in the study.
•5. Participant who hospitalized for rehabilitation at ISIC will be included in the study.

•1. Mental, psychiatric or cognitive disorder and /or pre-existing medical condition that might interfere with the outcomes.
•2. Pressure sores associated with osteomyelitis, malignancy, leprosy and HIV (+ve)
•3. Platelet dysfunction
•4. Arterial origin of the cutaneous ulcers.
•5. Active vasculitis,
•6. Systemic lupus erythematosus, cryoglobulinemia,
•7. Hematological abnormality or any coagulation abnormalities.
•8. Current use of anticoagulants and/or treatment with immunosuppressant drugs;
•9. Serum hemoglobin concentration <11 g/dL or hematocrit <34%;
•10. Participant taking drug which might interfere with the study intervention like Anti- neoplastic drugs, steroids, antibiotics etc.
•11. Drug or alcohol abuse..
•12. Patient who smokes will be excluded from the study.
•13. Diabetes (controlled/ Uncontrolled), uncontrolled hypertension, autoimmune disease, renal failure.

发起方