IRCT20231104059949N1招募中3 期
Comparison of the effect of endotracheal suction using two methods, endotracheal N-acetylcysteine and normal saline, on hemodynamic parameters and arterial blood gases in intubated patients under mechanical
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 90
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 years 至 60 years（—）
- 性别
- All
入选标准
- •Patients who are connected to mechanical ventilation for at least 48 hours and at most one week
- •Patients with endotracheal tubes
- •Patients who are between 20 and 60 years old
- •Patients who are hemodynamically stable (heart rate between 60-100 beats per minute, blood pressure between 160/100-110/60 mmHg, Spo2 more than 90%, urinary output more than 30 ml/hour)
- •Patients with normal electrolyte levels and no cardiac arrhythmia
- •Insensitivity to N-acetylcysteine and other drugs
- •Absence of pulmonary edema, chronic obstructive pulmonary diseases and asthma
- •Patients who do not have chest trauma or chest tube
- •Absence of brain edema, spinal cord injury, increased intracranial pressure
排除标准
- •Patients who are hemodynamically unstable (heart rate less than 60 beats per minute, blood pressure less than 100/60 mmHg, Spo2 less than 90%)
- •Any changes in mechanical ventilation settings during the study
- •Death of the patient
- •Lack of consent of the patient's family
- •Use of muscle relaxants and inotropic drugs during the study
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