Antioxidants in acute aluminum phosphide poisoning

Phase 2

Recruiting

• Conditions: Acute aluminum phosphide poisoning.; Toxic effect of pesticides

• Registration Number: IRCT20200724048192N1
• Lead Sponsor: Menoufia Faculty of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 September 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

History of taking aluminum phosphide tablet(s) and clinical manifestations of acute aluminum phosphide poisoning
Reliable identification of the compound either by the container brought by patient attendants or subsequent confirmation with positive silver nitrate test on gastric sample in case of oral route exposure

Exclusion Criteria

Patients less than 12 years old
Pregnant and lactating women
Patients suffering from chronic diseases (e.g. diabetes mellitus, cardiovascular diseases, and hepatic or renal failure)
Tablet(s) was/were dissolved in water before ingestion
Ingestion of air-exposed aluminium phosphide tablets
Time passed since ingestion more than 8 hours
Patient who refused to participate

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
All-cause mortality during hospital admission. Timepoint: At the end of the hospitalization period. Method of measurement: Clinical assessment.

Secondary Outcome Measures

Name	Time	Method
Proportion of patients requiring intubation. Timepoint: Before the intervention and one day after completion of the intervention. Method of measurement: Clinical evaluation.;Duration of ventilation. Timepoint: Before the intervention and one day after completion of the intervention. Method of measurement: Clinical evaluation.;Duration of hospitalization. Timepoint: At the end of the hospitalization period. Method of measurement: Clinical evaluation.