Effectiveness of acetylcysteine in ?rescue? therapy for Helicobacter pylori infection. Pilot Study - ND
- Conditions
- Duodenal and gastric ulcer recurrence with Helicobacter P. infectionMedDRA version: 9.1Level: LLTClassification code 10065231MedDRA version: 9.1Level: LLTClassification code 10051790
- Registration Number
- EUCTR2009-011979-76-IT
- Lead Sponsor
- POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
both genders, age > 18 years, persistent infection from Helicobacter pylori, at gastroscopy or 13C urea breath test, after 5 eradication therapies.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Verified allergies to the acetylcysteine or to the antibiotics to cure Helicobacter pylori, pregnancy, nursing.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: Effectiveness of acetylcysteine in ?rescue? therapy for Helicobacter pylori infection. Due to lytic action on the gastric mucus, the administration of acetylcysteine in the 7 preceding days the antibiotic therapy, after endoscopy with culture and consequent antibiotic susceptibility testing, would allow a best aggression of the Helicobacter from selected antibiotics.;Secondary Objective: ND;Primary end point(s): Helicobacter pylori eradication
- Secondary Outcome Measures
Name Time Method