Assessment of efficacy of N-Acetylecysteine plus standard quadruple therapy regimen in comparison to standard quadruple therapy regimen for H. pylori infection eradiacatio
Phase 2
- Conditions
- Helicobacter pylori.Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
- Registration Number
- IRCT201605201155N24
- Lead Sponsor
- Vice chancellor for research of Guilan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 46
Inclusion Criteria
All patients with peptic-like epigastric pain and dyspeptic symptoms, referred to the endoscopy unit and scheduled for upper GI endoscopy and with positive rapid urease test
Exclusion criteria: age<18 and >70, recent use of antibiotics, bismuth salts, or proton pump inhibitors (PPI), chronic use of nonsteroidal anti-inflammatory drugs or corticosteroids, gastric outlet obstruction, pregnancy, renal failure, gastric malignancy, and prior gastric surgery
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Eradocation of Helicobacter pylori. Timepoint: before initiate Intervention, two wk after finishing the intervention. Method of measurement: Urease breath test.
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: before initiating intervention, 2 wk after finishing the intervention. Method of measurement: physical examination.