Effect of N-acetylcysteine in the improvement of Aphthous
- Conditions
- Recurrent aphthous stomatitis.Recurrent oral aphthae
- Registration Number
- IRCT20180728040614N1
- Lead Sponsor
- Sari University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 46
Age group 16 to 45 years old
Diagnostic criteria for aphthous stomatitis
sufficient knowledge to understand the description provided for treatment
Legally the patients are able to complete their consent form
People who take suppressive drugs during the past month
People with Systemic Disease
People with syndromes such as Behcet's syndrome, which aphthous ulcer is one of the manifestations .
Patients who develop aphthous ulcers in areas other than labial and buccal mucosa
People with recurrent stomatitis Herpes form
People with recurrent major aphthous stomatitis
Patients with poor oral hygiene
Pregnant women
Antibiotic users
Patients with dentures
People who use other drugs to treat aphthous ulcer and in general people who cant stay or cant continue cooperation till end of research due to personal and social reasons
Smoking Individuals
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Diameter of eritmathous halo. Timepoint: Days zero (before entering the study); third; fifth and seventh. Method of measurement: Metal caliber.;Period of improvement. Timepoint: Days zero (before entering the study); third; fifth and seventh. Method of measurement: Visual Analogue Scale Questionnaire.
- Secondary Outcome Measures
Name Time Method The amount of pain. Timepoint: Days zero (before entering the study); third; fifth and seventh. Method of measurement: Visual Analogue Scale Questionnaire.