Resistance Training and Multiple Sclerosis

Phase 3

• Conditions: Multiple Sclerosis.; Other specified mental disorders due to known physiological condition; F06.8

• Registration Number: IRCT20120912010824N3
• Lead Sponsor: Kermanshah University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

history of at least two-year diagnosed RR-MS
EDSS =4
no other chronic diseases (metabolic, cardiovascular, renal, …)
no history of regular physical activity in the previous 6 months

Exclusion Criteria

No contracting COVID-19

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Indices Related to Blood Brain Barrier Permeability (matrix metalloproteinases (MMPs) and specific tissue inhibitors of MMPs, s100B). Timepoint: pre and post of exercise protocol. Method of measurement: blood sampling.

Secondary Outcome Measures

Name	Time	Method
Cognitive Performance. Timepoint: pre and post of exercise protocol. Method of measurement: The Brief International Cognitive Assessment for MS (BICAMS) was used to examine information processing speed and immediate verbal and visual recall. The BICAMS consists of the Symbol Digit Modalities Test (SDMT), California Verbal Learning Test-II (CVLT-II) and the Brief Visuospatial Memory Test- Revised (BVMT-R).